Neymar still has fears over foot injury ahead of World Cup

first_imgLights inside SMX hall flicker as Duterte rants vs Ayala, Pangilinan anew Green group flags ‘overkill’ use of plastic banderitas in Manila Sto. Niño feast P16.5-M worth of aid provided for Taal Volcano eruption victims — NDRRMC Neymar said this season has been the least he’s ever played, so he is rested for the World Cup that begins on June 14 in Moscow.He said what he misses the most about his Barcelona days was his friendship with Lionel Messi and Luis Suarez.Brazil’s first game at the World Cup is on June 17 against Switzerland. Serbia and Costa Rica are also in their group.ADVERTISEMENT Raptors fire coach Dwane Casey after another sweep by Cavs Volcano watch: Island fissures steaming, lake water receding MOST READ Jo Koy draws ire for cutting through Cebu City traffic with ‘wang-wang’ Scientists seek rare species survivors amid Australia flames Carpio hits red carpet treatment for China Coast Guard PLAY LIST 02:14Carpio hits red carpet treatment for China Coast Guard02:56NCRPO pledges to donate P3.5 million to victims of Taal eruption00:56Heavy rain brings some relief in Australia02:37Calm moments allow Taal folks some respite03:23Negosyo sa Tagaytay City, bagsak sa pag-aalboroto ng Bulkang Taal01:13Christian Standhardinger wins PBA Best Player award “I need to lose that fear as quickly as possible to arrive at the World Cup at my best,” Neymar said in an interview on Zico’s YouTube channel. “In the beginning we are hesitant about making the complete movement.”He cracked the fifth metatarsal that connects to the little toe in his right foot, and a week later, on March 3, he underwent surgery in Brazil. The diagnosis was he would be out for up to three months.FEATURED STORIESSPORTSGinebra beats Meralco again to capture PBA Governors’ Cup titleSPORTSAfter winning title, time for LA Tenorio to give back to Batangas folkSPORTSTim Cone, Ginebra set their sights on elusive All-Filipino crownThis week, Neymar returned to Paris to continue his rehabilitation, and is not expected to play for PSG, who signed him for a record 222 million euros (now $265 million) last August from Barcelona.The interview took place at his mansion in Mangaratiba, outside Rio de Janeiro. Sports Related Videospowered by AdSparcRead Next PSG’s Neymar reacts after the French Cup soccer final Paris Saint Germain against Les Herbiers at the Stade de France stadium in Saint-Denis, outside Paris, Tuesday, May 8, 2018. Paris Saint-Germain beat resilient third-division side Les Herbiers 2-0 to win the French Cup. (AP Photo/Francois Mori)SAO PAULO — Neymar still has fears weeks out from the World Cup in Russia about the right foot he broke.In an interview published on Friday, the Brazil and Paris Saint-Germain striker said treatment has worked “but there is always that fear of it (the injury) coming back.”ADVERTISEMENT In fight vs corruption, Duterte now points to Ayala, MVP companies as ‘big fish’ Jiro Manio arrested for stabbing man in Marikina Truck driver killed in Davao del Sur road accident Don’t miss out on the latest news and information. LATEST STORIES View commentslast_img read more

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Embrace Govt’s Green State Development Strategy – Minister Ferguson

first_imgMinister within the Public Infrastructure Ministry, Annette Ferguson, encouraged dozens of electrical contractors, suppliers and other stakeholders to adapt to Government’s ‘Green State Development Strategy’.The Minister was delivering the feature address at the opening of the Government Electrical Inspectorate’s (GEI) annual conference at the Umana Yana, Kingston on Thursday.Junior Public Infrastructure Minister Annette Ferguson“As we Embrace a Green Energy Sector to power a Green Economy, I would like you to also remember that this initiative by your Government is all-inclusive. It means that you, as electrical contractors, business owners and suppliers of electrical products, must follow these standards.”The Minister explained that there are several benefits to be had from the adaptation to a ‘Green State’.The conference, the Minister added, was intended to educate contractors on, “the benefits of a green economy, requirements for photovoltaic systems with grid-ties, changes of the National Electrical Code 2017, new requirements for temporary meter circuits, range of voltage offered by Guyana Power and Light (GPL), the new classes of electrical contractor licence and updates on the new list of approved electrical items, among others.”Meanwhile, the Ministry of the Presidency’s Department of the Environment, Stakeholder Management Coordinator (ag), Aretha Forde explained that “going green is not about a colour but rather a concept. The rest of the world is embracing a ‘green economy’ and in order for Guyana to advance, as we all would like to see, we need to get onboard.”She further noted that the ‘Green State Development Strategy’ (GSDS) is intended to be Guyana’s long-term national development plan.“This development plan will go along a green pathway. It will help us to realise green economies. The green economy is our final destination,” Forde explained.In addition, Forde identified the GSDS as different to the LCDS. She said the LCDS was sector-based, whereas Guyana kept its forests intact and received payments from Norway for doing so. On the other hand, according to Forde, “The GSDS is all-encompassing. It looks at every single sector within Guyana. It looks at economic development, natural resource extraction, social component, environment…”There were also presentations by the Fire Prevention Office of the Guyana Fire Service, on safety measures to be adopted when faced with electrical fires and more especially those resulting from a solar electrical installation.The Government Electrical Inspectorate is the watch guard for the electrical energy sector. Its primary roles are to issue permits for electrical installations, certify code compliant installations, inspect and test electrical installations, licence qualified electrical contractors, resolve disputes between public suppliers and consumers of electricity, investigate fires and electrical accidents and train and edify electrical contractors through the publication of manuals.last_img read more

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Teen’s body found hanging in bedroom at Tuschen

first_imgSeventeen-year-old Rosalyn Lima of Lot 739 Tuschen New Housing Scheme East Bank Essequibo on Saturday morning became Guyana’s latest suicide victim when her lifeless body was found by her elder sister, Franceline Lima, hanging from a bed sheet tied to a rafter in her bedroom.The Guyana Times understands that the discovery was made at around 05:15h.Prior to the discovery, Franceline was reportedly awakened by a noise, and later heard the teenager on the phone telling someone, “Alright, good”. Franceline said she got out of bed and noticed her sister walking around. Questioned, Rosalyn claimed she was going to the washroom.Franceline said she looked through a window and observed a car with two male occupants parked in front of their home. Upon realising that something was amiss, she ordered Rosalyn back into her bedroom. This instruction had greatly upset Rosalyn.A few minutes later, Franceline recalled hearing noise emanating from Rosalyn’s bedroom, but did not pay heed since it was normal for her to bang the walls when upset.After some time had elapsed, she checked on the teenager, only to make the gruesome discovery that Rosalyn had committed suicide. An aggrieved Franceline reportedly cut the sheet from the rafter and raised an alarm.“I saw her hanging (from) the roof and still I didn’t really realise what was happening. But then I touched her and she was cold, so I cut the sheet and I called out to my uncle. And when he came, he checked her and said that she was dead,” the grieving sister recounted.Franceline tearfully declared, “I shouldn’t have gotten up, or I should’ve let her go with them; then she would’ve been alive”.The girls’ mother, Angela Lima, is said to be presently in Brazil.Interestingly, Rosalyn’s Facebook page shows numerous posts of her indicting that she wanted to end her life. One post has even stated “mentally affected teen…or is it just a stage?”The teen’s body was taken to the Sandy’s Funeral Home to await a post-mortem.last_img read more

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Sevilla curse their luck after letting Bayern lead slip

first_imgVincenzo Montella said afterwards his players had not had luck on their side and there was some truth in that.Franck Ribery’s cross was heading wide until Jesus Navas dangled out a foot and Thiago Alcantara’s header would probably have been saved had it not been diverted by Sergio Escudero.But for all their energy, verve and aggression, Sevilla have shown this week they still lack the control to manage matches against elite opposition.Against Bayern, they led for only six minutes, allowing their opponents to reach half-time level when they could easily have been two goals down as Pablo Sarabia, Sevilla’s scorer, had planted an earlier, easier chance wide.“With that opportunity it was a pity,” Sarabia said. “I tried to adjust it to the maximum and I did not hit the target.”Against Barcelona they had conceded twice after holding a deserved 2-0 lead with just two minutes to go.“We were a little lacking this side of experience… how to talk to the referee, and to be focused on small details,” Sevilla striker Wissam Ben Yedder said.“We know that it will be very complicated because now we have to (score) two goals there but we know that everything is possible.”Bayern coach Jupp Heynckes said he believed the timing of his side’s equaliser, just before the break, was a psychological turning-point.Scoring twice at the Allianz Arena next week is not beyond Sevilla, who can take heart from the numerous occasions they broke through Bayern on Tuesday — but it is hard to see them keeping a clean sheet.After the second leg, they play Celta Vigo and Villarreal in La Liga before a reunion in the Spanish Cup final with Barcelona, who this time are likely to have Lionel Messi for 90 minutes.If they are knocked out by Bayern and lose to Barca, Sevilla will be relying on their league position to qualify for Europe next season — they currently sit seventh, only two points ahead of Girona.Bayern, meanwhile, know they will have to improve with striker Robert Lewandowski, whose name continues to be linked with Real Madrid, virtually anonymous.It was the 34-year-old Ribery who made the difference. “In the first half we were not well organised,” Ribery said.“We did not play in front, at the break the coach gave us a telling off. Seville is a very good team who plays very well in football, but we reacted well after the 1-0.“We must not believe that we are already in the semi-finals.”0Shares0000(Visited 1 times, 1 visits today) 0Shares0000Sevilla’s Spanish midfielder Pablo Sarabia covers his face during the UEFA Champions League quarter-final first leg football match between Sevilla FC and Bayern Munich at the Ramon Sanchez Pizjuan Stadium in Sevilla on April 3, 2018. © AFP / Jorge GUERREROSEVILLE, Spain, Apr 4 – Sevilla ended their Champions League quarter-final first leg against Bayern Munich wondering what might have been, just as they had against Barcelona three days earlier.They had chances and were the better side for large spells of their 2-1 defeat at the Ramon Sanchez Pizjuan Stadium, but Bayern, like Barcelona, needed only a moment to strike.last_img read more

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Reports – Arsenal to open talks with £30m-rated Argentine starlet

first_imgArsenal are set to open talks with the representatives of Argentine sensation Paulo Dybala this week, according to reports in Italy.The striker is currently one of the hottest properties in Europe, with his performances for Palermo attracting the attention of several clubs.Manchester City and Tottenham have been linked with summer swoops, while Juventus are also reportedly keeping tabs on the situation.However, according to Sky Italia, Arsenal have moved into pole position for the 21-year-old and are due to meet his representatives this week.Palermo are said to want around £30m for their star striker, who has hit 12 goals in Serie A this season.The Italian club would also reportedly prefer to sell Dybala to a foreign club, rather than league rivals Juventus. 1 Paulo Dybala in action for Palermo last_img read more

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GIVEN, McGEADY AND COLEMAN INCLUDED IN EURO SQUAD

first_imgSHAY Given and Aiden McGeady have been included in Martin O’Neill’s squad for the Euro 2016 campaign in France.Both players were fighting for a place in the last 23 – with Killybegs man Seamus Coleman the only Donegal certainty.But Co Derry man O’Neill has gone with experience and has stood by Given and McGeady. He has also included Shane Duffy and James McClean – and kept Robbie Keane.However Derry duo Darron Gibson and Eunan O’Kane miss out.Ireland lost 2-1 to Belarus in a friendly in Cork this evening. Given could do little about either goal.Ireland start their Euro 2016 campaign against Sweden in Paris on June 12th, before facing Belgium in Bordeaux on June 18th and finishing in Lille against Italy on June 22nd. SQUAD IN FULL:Goalkeepers: Darren Randolph, Shay Given, Keiren Westwood.Defenders: Seamus Coleman, Cyrus Christie, John O’Shea, Ciaran Clark, Shane Duffy, Richard Keogh, Robbie Brady, Stephen Ward.Midfielders: Glenn Whelan, James McCarthy, Jeff Hendrick, Wes Hoolahan, James McClean, Aiden McGeady, Stephen Quinn, David Meyler.Forwards: Shane Long, Jon Walters, Daryl Murphy, Robbie KeaneGIVEN, McGEADY AND COLEMAN INCLUDED IN EURO SQUAD was last modified: May 31st, 2016 by John2Share this:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Reddit (Opens in new window)Click to share on Pocket (Opens in new window)Click to share on Telegram (Opens in new window)Click to share on WhatsApp (Opens in new window)Click to share on Skype (Opens in new window)Click to print (Opens in new window)last_img read more

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Letterkenny U14 girls ‘blaze’ a trail against Tigers

first_imgUNDER 14 GIRLS IN DAZLING FORM: The U14 girls dawned the court against Andersontown Tigers for their first home game of the season on Sunday morning. This game was hot on the heels of their first seasonal BNI league game after the team travelled to Queens PEC on Saturday 12th November to secure the win and showed great commitment and willingness to learn, with the majority of the girls staying on in the Loreto Convent for their usual training session when arriving back in Letterkenny.The Blaze girls displayed a very good team performance in Queens PEC by controlling the game from the start. On Sunday, the Andersontown Tigers fixture on home court was a fast paced game from the start, with the away team scoring from the tip of.However, the home team proved the stronger side in the first quarter by finishing out with a score line 18 pts to 9 pts with Shannon Cunningham dominating the boards for Blaze and assisted by scores from Megan Mc Daid, Rhianna Devenney and Maria Kealy.In the second quarter, Sinead Otoo, Rachael Sullivan, Tiegan Smith and Emily Mullen all contributed to the score line, resulting in the home team finishing the first half with a 16 pt lead (HT Blaze 27 pts, Andersontown Tigers 11 pts).Tigers, recovering from their journey to Letterkenny, settled better into the 2nd half and were gaining strength minute by minute. Emily Rodgers Duffy consistently upset the Blaze defence with strong drives to the board and showed her athleticism under the boards.Megan Bonner, Kayleigh Mc Guinness and Annie Mc Clintock all worked hard in the 3rd quarter. Blaze, who were struggling for scores, were relieved when Maria Kealy’s 3 pointer found the net and gave the home team a much welcomed score.The 3rd quarter finished Blaze 36pts Andersontown Tigers 21pts. Not happy with the deficit, Andersontown Tigers increased the intensity in defence and put pressure on the home side.  Emily Rogers Duffy, again proving to be a strong force for the visiting team secured 8 points for her team.Sinead Otoo (Blaze)  remaining calm throughout, performed trojan work for her team at both sides of the court.Blaze were successful in keeping the lead against the Andersontown girls who displayed a “never beaten” attitude from start to finish. Blaze girls look forward to the return fixture when these 2 teams meet again.Thanks to all the supporters who came out to get behind the home team.Elsewhere, other weekend results Under 14 boys travelled to Queens and came away with a win with a slim margin of 28-26.Meanwhile, an under strength U18 boys team travelled to Ballyshannon. Points from Ian Bagasala and P J McBrearty brought the game to within 1 point.However, Ballyshannon rallied to win 40-28.  Under 16 boys were in action also against Andersonstown Tigers.In what was an extremely competitive game, the boys worked really hard and were unlucky to come away with a lose of 2 points.Letterkenny U14 girls ‘blaze’ a trail against Tigers was last modified: November 14th, 2016 by Mark ForkerShare this:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Reddit (Opens in new window)Click to share on Pocket (Opens in new window)Click to share on Telegram (Opens in new window)Click to share on WhatsApp (Opens in new window)Click to share on Skype (Opens in new window)Click to print (Opens in new window)Tags:AnderstownbasketballblazeGirlsletterkennySportTigersu14last_img read more

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Chelsea reported to have made enquiry about striker Remy

first_imgChelsea have made an enquiry about Loic Remy, Goal.com say.Remy, 27, is keen to leave QPR for a top-four club and wants to stay in London.With neither Chelsea nor Arsenal having made a firm move for the France striker, he recently agreed a move to Liverpool but the transfer collapsed.And it is claimed that the Blues are now showing an interest after Didier Drogba picked up an ankle injury. Related West London Sport story: Injured Drogba a doubt for Burnley game Remy spent last season on loan at NewcastleChelsea are set to table a bid of just over £30m for Roma defender Mehdi Benatia, La Gazzetta Dello Sport claim.Manchester United have also been linked with the 27-year-old Morocco international, with reports suggesting he is potentially for sale.And the Blues have been tipped to offer €38m for Benatia, which Roma are said to be inclined to accept.Chelsea boss Jose Mourinho wants Benatia, it is claimedMeanwhile, QPR are close to completing a deal to sign Jonathan de Guzman from Villarreal, Spanish newspaper Marca has reported.The Netherlands midfielder, 26, has been on loan at Swansea for the last two seasons and they are keen to sign him permanently.But Rangers boss Harry Redknapp was alerted to his potential availability when it became apparent Swansea were struggling to agree a deal.Rangers are willing to pay £7m and Marca say Villarreal are ready to complete the transfer. Related West London Sport story (9 August): QPR ready to agree £7m De Guzman dealQPR have indicated they will pay £7m for De GuzmanAC Milan plan to offer QPR £3m for Adel Taarabt, Sky Sport Italia have reported.Taarabt ended last season on loan at the Italian club and is desperate to join them on a permanent basis.And it is claimed that Kia Joorabchian, who has advised QPR on various transfer deals and acts as Taarabt’s representative, is due to meet Milan chief executive Adriano Galliani on Tuesday to discuss a potential deal.Rangers manager Harry Redknapp, who sold Taarabt to the R’s when he was Tottenham boss, has indicated that the player is determined to move on.Taarabt’s future is uncertain following his return to Rangers.Spurs would be entitled to a significant share of any transfer fee under the terms of the deal that took Taarabt to Loftus Road in the summer of 2010. Related West London Sport story: No cut-price Taarabt deal, QPR boss insists See also:Chelsea tipped to seal Benatia signing and sell keeper CechFulham among clubs interested in QPR’s Onuoha, report claimsFollow West London Sport on TwitterFind us on Facebooklast_img read more

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Live updates: Warriors vs. Raptors, Wednesday at 7:30 p.m.

first_imgJoin us for live news and analysis Wednesday at 7:30 p.m. for one of arguably the most anticipated Warriors game this season when Golden State faces the Toronto Raptors at Oracle.The Raptors (22-7) own the NBA’s best record and have already handed the Warriors an overtime loss two weeks ago in Toronto. However, some of the luster of their rematch could be lost if Kawhi Leonard (hip injury) can’t play Wednesday night. He’s listed as questionable.The Warriors (19-9) are on a four-game …last_img read more

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Scientists Must Avoid the Slippery Slope of Designer Babies

first_imgWhy Scientists Must Reject Tinkering with the Human Genome, Even for Beneficial Purposesby Dr Jerry BergmanA Chinese geneticist, Dr He Jiankui, has caused a firestorm for modifying babies’ genes using a technology called the CRISPR/Cas9 gene editing tool.[1] Professor Jiankui is an associate professor in the Department of Biology of the Southern University of Science and Technology in Shenzhen, China. By using intelligent design to modify natural genes, the well-educated Chinese scientist hoped to improve the genetic package in two girls. CRISPR-Cas9 exploits existing genetic tools and technology, such as bacteriophages, that were designed by God to perform specific tasks. Ironically, evolutionists believe a massive number of largely random mutations, without the help of any intelligence, turned single celled creatures, such as bacteria, into modern humans. We evolved by mistake, they believe, with no design or plan.[2]Uncharted TerritoryIn short, CRISPR and other technologies allow technicians to bring in genes from outside of the cell and incorporate them at specific locations inside a host cell. The report on the experiment said that Professor He Jiankui “helped make the world’s first genetically edited babies—twin girls by the pseudonyms Lulu and Nana—by altering their DNA while they were embryos to become resistant to future HIV infection.”[3] One major concern was the possibility that gene editing could have unforeseeable negative consequences down the road. The gene altering could adversely affect other genes, or may adversely affect the immune system. In short, it is an experiment into uncharted territory that could have disastrous effects on the twins in the future.It may do only what it is designed to do: prevent them from contracting AIDS in the future, something we will not know unless they are exposed to the HIV virus after they are born. No one knows, and we will not know, until their lifespan is spent. It could also have negative consequences that we will never know about in these two girls, and will not know until we have a large enough sample to make some determination of the possible results, good or bad.Human Guinea PigsAll drugs have negative consequences called side effects. Some are mild, others lethal, but many are rare and depend on environmental and individual genetic contingencies of the drug recipient. The girls are guinea pigs and could be expected to blame the gene transplant on some problem they may have which actually had nothing to do with the genetic changes Professor He induced. Or they may suspect, without ever knowing for sure, that some problem they develop as they grow older was caused by the transplant.[4]Pandora’s BoxOne problem is that these CRISPR genetic changes are now in their germ cells, and will be passed on to the next generation, and the next as well, for who knows how long. These concerns were one of several reasons for the outrage, and the “response from the scientific community was immediate and censorious.”[5] One of their concerns is that Professor He “put children in danger with his experiments.”[6] Furthermore, leading figures in the scientific and legal community, no doubt remembering the sadistic Nazi medical experiments,called his work “unconscionable,” “not morally or ethically defensible,” “deeply disturbing,” “monstrous.” People questioned [Professor] He’s motives for the experiment and accused him of seeking fame and fortune—particularly when the Chinese researcher enlisted an American PR company to help release YouTube videos explaining his work. Since [Dr] He’s announcement, Chinese officials have placed him under house arrest in Shenzhen.[7]The Ghost of Nazi Medical ExperimentationThe concerns in this case are reminiscent of the experiments carried out by the scientists and professors in Nazi Germany that we today realize were often of little use, some even foolish, and always unethical. These experiments were attempted by highly qualified doctors, such as Josef Mengele, “Doctor Death,” best known for conducting morbid experimenting on humans. Mengele earned a PhD in anthropology from the University of Munich and also a doctorate in medicine (MD) from the University of Frankfurt, graduating cum laude.[8] In one case, he attempted to cause a person’s eyes to turn blue by injecting blue dye into them. Mengele used the same indigo blue dye used today to dye blue jeans!The widespread press reports on the CRISPR genetic alterations will insure that these medical techniques are well known. The cover story of the January, 14, 2019 Time Magazine boasted “Gene editing, Uterus transplants, three biological parents: The Future of Babies.”[9]It is significant that Professor He’s graduate training was in America. He received his Ph.D. in Biophysics under the supervision of Professor Michael W. Deem at Rice University. After completing his Ph.D., he did a postdoc with Professor Stephen Quake at Stanford University.Good IntentionsThe trial recruited couples who wanted to have children and, in order to participate, the man had to be HIV-positive and the woman uninfected.[10]  Professor He obtained the couple’s sperm and eggs to use for the in vitro fertilization, then edited the embryos’ genomes using CRISPR/Cas9. The editing targeted the CCR5 gene, which codes for a protein that HIV-1 uses to enter T-cells. He then implanted the edited zygotes in the womb of the woman who gave birth to twin girls in November of 2018.If the CCR5 gene is mutated, the AIDS virus is unable to enter white blood cells called T-cells, thus the person with the mutated gene is believed to be immune to AIDS. The specific mutation in the gene (CCR5 Δ32) is found in a few people naturally, and this confers innate resistance to HIV-1.[11] CCR5 Δ32 is a 32-base-pair deletion (Δ means deletion) that introduces a premature stop codon into the CCR5 receptor locus, resulting in a nonfunctional receptor. The CCR5 receptor is required for M-tropic HIV-1 virus entry, the main virus that causes AIDS. M-tropic is the macrophage strain of HIV-1. A macrophage is a large phagocytic cell located either in tissues or with other mobile white blood cells, where they accumulate at sites of infection. It is a phagocytic cell, meaning it “eats” bacteria, pathogens or cellular debris.How CRISPR/Cas9 WorksCRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats, and Cas9 is a gene silencer. The type II CRISPR mechanism is unique compared to other CRISPR systems, as only one Cas protein (Cas9) is required for gene silencing, which in this case silenced the CCR5 gene. This gene constructs the CCR5 protein receptor that is located on the cell wall of the T-Cell. In his experiment, Professor He has not introduced a new gene into the cell, but has caused damage to silence a specific gene that produces a protein that migrates to the cell surface of T-Cells involved in the immune system. The CCR5 protein functions as a receptor for chemokines, which are chemical messengers. Known or potential side effects of a damaged CCR5 receptor include impaired immune effectiveness.CRISPR genes are essential for various tasks including to achieve adaptive immunity in certain bacteria and archaea, enabling the organisms to respond to, and eliminate, certain invading genetic material, such as in viruses. Three types of CRISPR mechanisms have been identified so far, and type II is currently the most studied. Type II cuts invading DNA from viruses or plasmids into small fragments, and then incorporates the fragments into a CRISPR locus (meaning location) amidst a series of short (around 20 base pair) repeats.The loci targeted are then transcribed, meaning the DNA makes messenger RNA (mRNA). The mRNA transcripts are then used to generate small RNAs (crRNA – CRISPR RNA) that are used to guide effector endonucleases. These are enzymes that target invading virus DNA strands based on sequence complementarity. Professor He’s research used Transcription activator-like effector nucleases (TALEN) restriction enzymes that can be engineered to cut very specific sequences of DNA, in this case the gene that makes the CCR5 T-Cell receptor. This probably-too-brief review is presented to help illustrate how complex the designed system is.Where Now?A major problem is that once these techniques are available to the scientific community, they will likely be used, and no doubt at times abused as well. The issue is, as a Murphy-style proverb quips, “Once you open a can of worms, the only way to re-can them is to get a bigger can.” Abuse by irresponsible scientists tinkering with designer genes could potentially affect not only the twin girls, but the entire human population. It sets loose heritable changes that, if beneficial to recipients, turns humanity into haves and have-nots. The have-nots could be treated as second-class citizens or, worse, undesirables. If deleterious, humanity will be stuck with irreversible damage inside the human genome. Both possibilities lead to a slippery slope that all scientists must determine to reject from the outset. [1] https://www.youtube.com/watch?v=2pp17E4E-O8[2] Lee, Sophia. 2019. A Question of Ethics. World. 34(1): 51-53. January 9. Online at https://world.wng.org/2019/01/a_question_of_ethics.[3] Lee, Sophia. 2019. A Question of Ethics. World. 34(1): 51. January 9. On line at https://world.wng.org/2019/01/a_question_of_ethics.[4] Cox, David Benjamin. 2015. Therapeutic genome editing: prospects and challenges. Nature Medicine  21:121–131.[5] Lee, Sophia. 2019.[6] Lee, Sophia. 2019.[7] Lee, Sophia. 2019.[8] Bergman, Jerry. Hitler and the Nazi Darwinian Worldview: How the Nazi Eugenic Crusade for a Superior Race Caused the Greatest Holocaust in World History. 2012. Kitchener, Ontario, Canada: Joshua Press.[9] Time Magazine. 193(1); 32-45. January 14, 2019.[10] Marchione, Marilyn. 2018. Chinese researcher claims first gene-edited babies. November 26. https://www.apnews.com/4997bb7aa36c45449b488e19ac83e86d.[11] Belluck, Pam.  2018. “Chinese Scientist Who Says He Edited Babies’ Genes Defends His Work”. The New York Times. https://www.nytimes.com/2018/11/28/world/asia/gene-editing-babies-he-jiankui.html. November 28.Dr. Jerry Bergman has taught biology, genetics, chemistry, biochemistry, anthropology, geology, and microbiology at several colleges and universities including for over 40 years at Bowling Green State University, Medical College of Ohio where he was a research associate in experimental pathology, and The University of Toledo. He is a graduate of the Medical College of Ohio, Wayne State University in Detroit, the University of Toledo, and Bowling Green State University. He has over 1,300 publications in 12 languages and 40 books and monographs. His books and textbooks that include chapters that he authored, are in over 1,500 college libraries in 27 countries. So far over 80,000 copies of the 40 books and monographs that he has authored or co-authored are in print. For more of his articles on CEH, see his Author Profile.(Visited 269 times, 1 visits today)FacebookTwitterPinterestSave分享0last_img read more

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